Chicken and Spinach Casserole with Cream Cheese Recipe

Get ready to fall in love with dinner all over again! This Chicken and Spinach Casserole with Cream Cheese is an absolute weeknight sensation, blending savory chicken, luscious cream cheese, and fresh spinach into a cheesy, hearty bake that’s pure comfort in every bite. Whether you’re serving it up for a cozy family meal or a casual get-together, it’s the kind of dish that begs for second helpings and always disappears fast. Trust me, this is the kind of casserole you’ll crave on chilly evenings or anytime you need something warm and satisfying!

Ingredients You’ll Need

One of my favorite things about this Chicken and Spinach Casserole with Cream Cheese is how it uses ingredients you probably already have in your kitchen. Every element here helps build flavor, add creamy texture, or create that signature golden top—making each bite as delicious as the last.

• Chicken breasts: Opt for large, boneless, skinless ones—they’ll cook evenly and soak up all the flavors!
• Olive oil: Divided between the marinade and the spinach, it helps keep everything juicy while adding subtle richness.
• Garlic: Minced for a bold, aromatic punch that infuses the entire casserole.
• Italian seasoning: This herby blend brings classic Mediterranean notes to the dish.
• Salt: Essential for seasoning the chicken just right.
• Black pepper: Adds just the right amount of warmth and bite.
• Fresh spinach: Wilts down beautifully to add color and a nutritious boost.
• Cream cheese: Softened for easy mixing, it’s what makes the casserole irresistibly creamy.
• Shredded mozzarella: Divided for gooey, bubbly layers—don’t skimp!
• Parmesan cheese (optional): For an extra savory, nutty finish on top.

How to Make Chicken and Spinach Casserole with Cream Cheese

Step 1: Prep the Oven and Baking Dish

Let’s start off on the right foot—preheat your oven to 400°F and grab your favorite 9×13 inch baking dish. Give it a generous coating of butter or a quick spritz of cooking spray, and set it aside. This ensures nothing sticks and that perfect golden crust forms!

Step 2: Slice and Pound the Chicken

Take your chicken breasts and carefully slice them in half horizontally to make cutlets. If they’re a bit uneven, just use a rolling pin or meat mallet to gently pound the thicker parts until everything’s the same thickness. This trick means the chicken will bake evenly and stay juicy throughout.

Step 3: Marinate the Chicken

In a big bowl, whisk together 1 tablespoon of olive oil, the minced garlic, Italian seasoning, salt, and pepper. Toss your chicken cutlets in the marinade, making sure every piece gets coated. Cover the bowl and let it chill for at least 15 minutes in the fridge—this quick marinade packs the chicken with tons of flavor.

Step 4: Wilt the Spinach

Heat the last tablespoon of olive oil in a large skillet over medium heat. Pile in the fresh spinach and stir frequently. Within 2-3 minutes, it’ll wilt down dramatically—don’t worry, it’s exactly what you want! Set the cooked spinach aside to cool slightly.

Step 5: Make the Creamy Filling

Grab a mixing bowl and beat the softened cream cheese until it’s smooth. Now, fold in your wilted spinach, half a cup of mozzarella, and Parmesan if you’re using it. Give it a good mix. This creamy combo is the heart of Chicken and Spinach Casserole with Cream Cheese, delivering that decadent, cheesy magic!

Step 6: Arrange the Chicken

Pull the chicken from the marinade, letting any excess drip off. For extra flavor (totally optional), sear the cutlets in your skillet for 1–2 minutes per side. Then arrange them in a single, even layer in your prepared baking dish, ready to be topped!

Step 7: Add the Cream Cheese Mixture and Cheese

Spread the spinach and cream cheese mixture generously over all the chicken cutlets, smoothing it out so every piece is covered. Sprinkle the remaining mozzarella cheese on top, and a little extra Parmesan if you’re feeling fancy.

Step 8: Bake and Rest

Slide your casserole into the oven and bake for 20–30 minutes. You’re looking for bubbly, golden cheese and perfectly cooked chicken—check that juicy center to be sure! Let it rest for 5 minutes before serving so everything stays sliceable and those flavors meld together beautifully.

How to Serve Chicken and Spinach Casserole with Cream Cheese

Garnishes

The finishing touches make all the difference! I love scattering chopped fresh parsley or basil across the top for a burst of color and freshness. A light sprinkle of extra Parmesan or even a pinch of red pepper flakes adds zing and makes the presentation pop.

Side Dishes

Because Chicken and Spinach Casserole with Cream Cheese is rich and satisfying, pair it with something bright and simple. Think crisp green salads, roasted vegetables, or some fluffy rice pilaf. Garlic bread is always a welcomed addition—perfect for mopping up that creamy sauce!

Creative Ways to Present

If you want to impress, spoon individual portions into ramekins for a dinner party, or tuck slices into warm pita bread with greens for a hearty sandwich twist. You can even top each serving with a sunny-side-up egg for a decadent brunch treat!

Make Ahead and Storage

Storing Leftovers

Transfer any leftovers into an airtight container and pop them in the fridge. They’ll stay fresh and delicious for up to three days. The flavors actually deepen overnight, making your second helping even better!

Freezing

Good news: Chicken and Spinach Casserole with Cream Cheese freezes wonderfully! Just wrap individual portions tightly with foil or plastic wrap before transferring to a freezer-safe container. They’ll keep well for up to two months.

Reheating

Reheat refrigerated slices in the oven at 350°F until heated through, or microwave individual portions for 1–2 minutes. If reheating from frozen, thaw overnight in the fridge first, then bake—this keeps the cheese gooey and the chicken moist!

FAQs

Can I use frozen spinach instead of fresh?

Absolutely! If using frozen spinach, thaw and squeeze out as much excess liquid as possible before mixing it with the cream cheese. This prevents the casserole from becoming watery and keeps the flavors rich.

What’s the best way to tell if the chicken is fully cooked?

The easiest way is to check with a meat thermometer; the center should reach 165°F. If you don’t have one, just cut into the thickest piece—the meat should be white and juices clear, with no pink remaining.

Can I make Chicken and Spinach Casserole with Cream Cheese ahead of time?

Yes! You can assemble everything (except for the final cheese topping) up to a day ahead, cover, and store in the fridge. Just add the remaining cheese right before baking, and extend the baking time by a few extra minutes if baking straight from the fridge.

Is there a dairy-free substitute for the cream cheese?

For a dairy-free version, you can swap in your favorite plant-based cream cheese and vegan mozzarella. The results are still creamy and satisfying, ensuring everyone can enjoy Chicken and Spinach Casserole with Cream Cheese.

How can I add more vegetables?

Feel free to add thinly sliced mushrooms, roasted bell peppers, or even blanched broccoli into the cream cheese mixture. It’s a flexible recipe that welcomes extra veggies and color!

Final Thoughts

If you’ve been searching for something easy yet special to bake for dinner, let Chicken and Spinach Casserole with Cream Cheese become your new go-to. It’s cozy, versatile, and packed with flavor—everything a weeknight comfort food should be. Give it a try and share the magic with the people you love!

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